帅心涛，化学与化工学院教授，中山医学院双聘教授，中山医学院生物医学工程中心负责人，光电及功能复合材料研究院“纳米生物技术”平台PI。以纳米医学技术为平台的肿瘤诊断及治疗研究，主要涉及肿瘤显像纳米探针、抗癌药物和核酸（例如：基因及RNAi等）的高效靶向传输等。
中文名帅心涛
民族汉族
国籍中国
毕业院校北京理工大学
职业学者
代表作品Biodegradable Supra-molecular Vehicle Showing Combined Good Biocompatibility and High Gene Transfection Efficiency
专业方向以聚合物纳米医学技术为平台的疾病诊断及治疗研究
任职院校中山大学
工作经历
2005年6月开始：中山大学化学与化工学院高分子所教授。
2003年6月-2005年5月：美国凯斯西储大学研究员（研究助教授级）。
2002年1月-2003年5月：德国马尔堡大学洪堡学者。
2001年1月-2001年12月：美国北卡州立大学访问学者。
2000年10月-2000年12月：中国科学院工程塑料国家工程研究中心，任研究三室主任。
1998年2月-2000年9月：中国科学院化学研究所，任副研究员及研究组长。其间赴日本名古屋大学及东京工业大学做访问研究一年。
1996年10月-1997年12月：波兰科学院聚合物化学研究所博士后。
教育背景
1993年3月-1996年10月：北京理工大学化工与材料学院学习，获博士学位。
1986年9月-1993年2月：北京理工大学化工与材料学院学习，获学士及硕士学位。
学术积累
一直从事新型生物降解及生物相容聚合物的合成及应用研究，近年来主要从事聚合物纳米医用材料的研究，在抗癌药物和核酸的传输以及肿瘤显像等方面取得一系列研究成果。
在包括《Macromolecules》、《Bioconjugate Chem.》、《Biomacromolecules》、《Chem. Mater.》、《Angew. Chem.》、《Chem. Commun.》、《Adv. Mater.》、《J. Controlled Release》、《Biomaterials》、《J. Biomed. Mater. Res.》等学术刊物上发表论文40多篇（其中，SCI收录论文35篇），被国内外同行在SCI刊物上引用100多篇次（扣除自引）。
现为J. Controlled Release等7个国际学术期刊的审稿人。与欧、美、日等国家高水平研究室建立了稳固的学术联系，为开展高水平的国际合作奠定了坚实的基础。
近5年来，作为负责人承担2项纳米医学研究领域的国家自然科学基金项目。目前除了一项国家自然科学基金项目在研外，还承担一项中山大学高层次引进人才基金项目。
主要论著
近5年来主要论著（SCI影响因子4以上的论文）：
1.D. Cheng,G. Hong,W. Wang,R. Yuan,H. Ai,J. Shen
*
,B. Liang,J. Gao,X. Shuai*
，“Nonclustered magnetite nanoparticle encapsulated biodegradable polymeric micelles with enhanced properties for in vivo tumor imaging”，J. Mater. Chem.
,DOI:10.1039/C0JM03783D.（IF=4.795）2.N. Cao,D. Cheng,S. Zou,H. Ai,J. Gao,
X. Shuai*
，“The synergistic effect of hierarchical assemblies of siRNA and chemotherapeutic drugs co-delivered into hepatic cancer cells”，Biomaterials
,Doi:10.1016/j.biomaterials.2010.11.061.（IF=7.365）3. J. Dai,S. Zou,Y. Pei,D. Cheng,H. Ai,
X. Shuai*
，“Polyethylenimine-grafted Copolymer of Poly(L-lysine) and Poly(ethylene glycol) for Gene Delivery”，Biomaterials
,Doi:10.1016/j.biomaterials.2010.10.044.（IF=7.365）4. G. Liu,Z. Wang,J. Lu,C. Xia,F. Gao,Q. Gong,B. Song,X. Zhao,
X. Shuai
,X. Chen,H. Ai,Z. Gu，“Low molecular weight alkyl-polycation wrapped magnetite nanoparticle clusters as MRI probes for stem cell labeling and in vivo imaging”，Biomaterials
,2011,2,528-537. （IF=7.365）5. W. Zhang,Y. Li,L. Liu
*
,Q. Sun,X. Shuai*
,W. Zhu,Y Chen*
，“Amphiphilic Toothbrushlike Copolymers Based on Poly(ethylene glycol) and Poly（ε-caprolactone) as Drug Carriers with Enhanced Properties”，Biomacromolecules
,2010,
11 ,1331-1338.（IF=4.502）6. B. Liang,M. He,C. Chan,Y. Chen,X. Li,Y. Li,D. Zheng,M. Lin,H. Kung,
X. Shuai*
,Ying Peng*，“The Use of Folate-PEG-grafted-hybranched-PEI Nonviral Vector for the Inhibition of Glioma Growth In The Rat”，Biomaterials
2009,30,4014-4020.（IF=7.365）7. J. Lu,S. Ma,J. Sun,C. Xia,C. Liu,Z. Wang,X. Zhao,F. Gao,Q. Gong,B. Song,
X. Shuai
,Hua Ai,Zhongwei Gu，“Manganese ferrite nanoparticle micellar nanocomposites as MRI contrast agent for liver imaging”，Biomaterials
2009,30,2919-2928.（IF=7.365）8. G. Chen*,W. Chen,Z. Wu,R. Yuan,Hua Li,J. Gao,X. Shuai*，“MRI-visible polymeric vector bearing CD3 single chain antibody for gene delivery to T cells for immunosuppression”，Biomaterials 2009,30,1962-1970.（IF=7.365）
9. H. Ai,C. Flask,B. Weinberg,
X. Shuai
,M. D. Pagel,D. Farrell,J. Duerk,J. Gao，“Magnetite-loaded polymeric micelles as novel magnetic resonance probe”，Adv. Mater.
2005,17,1949-1952.（IF=8.379）10. S. Mao,
X. Shuai
,F. Unger,and T. Kissel，“Synthesis and characterization of water-soluble poly (ethylene glycol)-graft-trimethyl chitosan block copolymers and their application as insulin delivery carriers”，Biomaterials
2005,26,6343-6356.（IF=7.365）11.
X. Shuai
,T. Merdan,F. Unger,T. Kissel，“Biodegradable Supra-molecular Vehicle Showing Combined Good Biocompatibility and High Gene Transfection Efficiency”，Bioconjugate Chem.
2005,16,322-329.（IF=4.35）12. N. Nasongkla†,X. Shuai†,H. Ai,J. Gao，“cRGD-functionalized micelle (cRGD-PEG-PCL) for targeted doxorubicin delivery to tumor neovasculature”，Angew. Chem. Int. Edi. 2004,43,6323-6327.（共同第1,IF=11.829）
13. Y. Zhao,
X. Shuai
,C. Chen,F. Xi，“Synthesis of star block copolymers from dendrimer initiators by combing ring-opening polymerization and atom transfer radical polymerization”，Macromolecules
2004,37,8854-8862.（IF=4.539）14.
X. Shuai
,H. Ai,N. Nasongkla,S. Kim,and J. Gao，“Micellar Carriers Based on Block Copolymers of Poly(e-caprolactone) and Poly(ethylene glycol) for Doxorubicin Delivery”，J. Controlled Release
2004,98,415-426.（IF=5.949）15.
X. Shuai
,T. Merdan,and T. Kissel，“Core-crosslinked Polymeric Micelles as Paclitaxel carriers”，Bioconjugate Chem.
2004,15,441-448.（IF=4.35）16. Y. Zhao,
X. Shuai
,C. Chen,F. Xi，“Synthesis of novel dendrimer-like star block copolymers with definite number of arms by combination of ROP and ATRP”，Chem. Commun.
2004,14,1608-1609.（IF=5.504）17.
X. Shuai
,T. Merdan,F. Unger,W. Matthias,and T. Kissel，“Novel Biodegradable Ternary Copolymers hy-PEI-g-PCL-b-PEG: Synthesis,Characterization and Potential as Efficient Non-viral Gene Delivery Vectors”，Macromolecules
2003,36,5751-5759.（IF=4.539）18. Y. Zhao,
X. Shuai
,C. Chen,F. Xi，“Synthesis and Characterization of Star-Shaped Poly(L-lactide)s Initiated with Hydroxyl-Terminated Poly(Amidoamine) (PAMAM-OH) Dendrimers”，Chem. Mater.
2003,15,2836-2843.（IF=5.368）19. M. Wei,
X. Shuai,
A. E. Tonelli，“Melting and Crystallizatioin Behavior of Biodegradable Polymers Enzymatically Coalesced from Their Cyclodextrin Inclusion Complexes”，Biomacromolecules
2003,4,783-792.（IF=4.502）20.
X. Shuai
,F. Porbeni,M. Wei,T. Bullions,A. E. Tonelli，“Stereo-selectivity in the Formation of Inclusion Complexes of Poly（3-hydroxybutyrate)s with Cyclodextrins”，Macromolecules
2002,35,3778-3780.（IF=4.539）21. Y. Na,Y. He,
X. Shuai
,Y. Kikkawa,Y. Doi,and Y. Inoue，“Compatibilization Effect of Poly(e-caprolactone)- b-Poly(ethylene glycol) Block Copolymers and Phase Morphology Analysis in Immiscible Poly(lactide)/ Poly(e-caprolactone) Blends”，Biomacromolecules
2002,3,1179-1186.（IF=4.502）22.
X. Shuai
,F. Porbeni,M. Wei,T. Bullions,A. E. Tonelli，“Formation of Inclusion Complexes of Poly（3-hydroxybutyrate)s with Cyclodextrins 1: Immobilization of Atactic Poly(R,S-3-hydroxybutyrate) and Miscibility Enhancement between Poly(R,S-3-hydroxy butyrate) and Poly(e-caprolactone）”，Macromolecules
2002,35,3126-3132.（IF=4.539）23.
X. Shuai
,F. Porbeni,M. Wei,T. Bullions,A. E. Tonelli，“Inclusion Complex Formation between α，γ-Cyclodextrins and a Triblock Copolymer and the Cyclodextrin Type-Dependent Microphase Structures of their Coalesced Samples”，Macromolecules
2002,35,2401-2405. （IF=4.539）24.
X. Shuai
,M. Wei,F. Porbeni,A. E. Tonelli，“Formation of and coalescence from the inclusion complex of a biodegradable block copolymer and a-cyclodextrin2: A novel means to modify the biodegradation behavor of biodegradable block copolymers”，Biomacromolecules
2002,3,201-207.（IF=4.502）25.
X. Shuai
,F. Porbeni,M. Wei,I. Shin & A. E. Tonelli，“Formation of and coalescence from the inclusion complex of a biodegradable block copolymer and a-cyclodextrin: A novel means to modify the phase structure of biodegradable block copolymers”，Macromolecules
2001,34,7355-7361.（IF=4.539）26. Y. He,J. Li,
X. Shuai
,Y. Inoue，“Reversible thinning/thickening phenomenon of polymer blends in aqueous media”，Macromolecules
2001,34,8166-8172.（IF=4.539）27. Y. He,
X. Shuai
,A. Cao,K. Kasuya,Y. Doi,Y. Inoue，“Enzymatic biodegradation of synthetic atactic P(R,S-hydroxybutyrate) induced by amorphous polymer and the enzymatic degradation temperature window of amorphous systems”，Biomacromolecules
2001,2,1045-1051.（IF=4.502）28. Y. He,He,
X. Shuai
,A. Cao,K. Kasuya,Y. Doi,Y. Inoue,"Enzymatic biodegradation of chemosynthetic atactic P（3HB) enhanced by an amorphous non-biodegradable polymer: blend of atactic P（3HB) with PMMA",Macromol. Rapid Comm.
,
2000,21: 1277-1281.（IF= 4.146）相关推荐
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